Onion or the treatment of ovarian cancer-3u8895

As everyone knows for onions or beneficial to the treatment of ovarian cancer is beneficial to onion or ovarian cancer, by regulating the tumor microenvironment of tumor associated macrophages (TAMs) in tumor play an important role in the development of M2, polarized targeting TAMs before tumor activation or TAMs is expected to become the effective method for treatment of cancer patients. Previous studies have shown that A (ONA), a natural low molecular weight compound isolated from onion, can inhibit the polarization of M2 macrophages. In this study, the researchers sought to investigate whether ONA has a protective effect against ovarian cancer in vivo and in vitro. The results showed that ONA could decrease the proliferation of ovarian cancer cells induced by co culture with macrophages in vitro by Del. In addition, the researchers also found that ONA can directly inhibit the proliferation of cancer cells. The combination of ONA and anticancer drugs also results. ONA in ovarian cancer cells significantly inhibited the activation of signal transducer and transcription factor 3 (STAT3), which is associated with cell proliferation and chemoresistance. In addition, the use of single or combination therapy in the mouse model of ovarian cancer may inhibit tumor progression and prolong the survival time of mice. Therefore, ONA may be used as an adjunctive therapy for the treatment of ovarian cancer.相关的主题文章: